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WHEN MARGINS WIDE – RADIATION THERAPY
NOT INDICATED IN INTRADUCTAL CANCER Dr. Mel Silverstein and his colleagues at the University of Southern California School of Medicine, reported that ductal carcinoma in-situ (DCIS) is unlikely to recur if
completely excised. The probability of recurrence at 8 years after undergoing lumpectomy with or without radiation therapy demonstrated that when DCIS was removed with at least a 1cm margin width, there was no benefit
from postoperative radiation therapy. When the margin width was < 1mm, there is significant benefit from radiation therapy. Dr. Silverstein re-excised the surgical site to attain wider margins.(Silverstein MJ et
al. The influence of margin width on local control of ductal carcinoma in situ of the breast. New England Journal of Medicine 340(19):1455-61, May 13, 1999.) |
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